Related Experiment Video

Updated: Jan 20, 2026

Peering into the Dynamics of Social Interactions: Measuring Play Fighting in Rats
15:01

Peering into the Dynamics of Social Interactions: Measuring Play Fighting in Rats

Published on: January 18, 2013

15.9K

Fimasartan: A new armament to fight hypertension

Akshyaya Pradhan1, Vikas Gupta1, Rishi Sethi1

  • 1Department of Cardiology, King George Medical University, Lucknow, Uttar Pradesh, India.

Journal of Family Medicine and Primary Care
|August 30, 2019
PubMed

Insights

Fimasartan, a potent Angiotensin Receptor Blocker, effectively treats hypertension for over 24 hours. Clinical evidence supports its use, showing benefits for kidney health and diabetes management.

Area of Science:

  • Cardiovascular medicine
  • Pharmacology

Background:

  • Hypertension represents a significant global public health challenge.
  • Angiotensin Receptor Blockers (ARBs) are crucial in managing hypertension.

Purpose of the Study:

  • To review the pharmacology and clinical evidence of fimasartan.
  • To provide a concise overview of earlier ARBs.

Main Methods:

  • Literature review of clinical studies on fimasartan.
  • Pharmacological analysis of fimasartan's mechanism and duration of action.

Main Results:

  • Fimasartan demonstrates potent and long-lasting (over 24 hours) angiotensin receptor blockade.
  • Clinical studies confirm fimasartan's efficacy in hypertension pharmacotherapy.
  • Fimasartan exhibits renoprotective properties and benefits in diabetic patients.

Conclusions:

  • Fimasartan is an effective and well-tolerated ARB for hypertension treatment.
  • Its pharmacological profile suggests advantages in patient management, including those with diabetes and kidney issues.

Keywords:
Angiotensin receptor blockerclinical studiesfimasartanhypertensionpharmacokinetics

More Related Videos

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion08:35

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

4.0K
Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug05:57

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug

Published on: May 17, 2024

1.2K

Related Concept Videos

Peering into the Dynamics of Social Interactions: Measuring Play Fighting in Rats15:01

Peering into the Dynamics of Social Interactions: Measuring Play Fighting in Rats

Play fighting in the rat involves attack and defense of the nape of the neck, which if contacted, is gently nuzzled with the snout. Because the movements of one animal are countered by the actions of its partner, play fighting is a complex, dynamic interaction. This dynamic complexity raises methodological problems about what to score for experimental studies. We present a scoring schema that is sensitive to the correlated nature of the actions performed. Two experiments illustrate how these...
15.9K
Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion08:35

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Here, we present a protocol for renal sympathetic denervation (RDN) in mice with hypertension induced by Angiotensin II infusion. The procedure is repeatable, convenient and allows to study the regulatory mechanisms of RDN on hypertension and cardiac...
4.0K
The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension05:57

The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension

Here, we present a protocol to induce H-type hypertension and evaluate the antihypertensive effects of Huotan Jiedu Tongluo decoction (HTJDTLD) administered intragastrically. In rats with H-type hypertension, HTJDTLD had effective antihypertensive effects, possibly associated with inhibition of endoplasmic reticulum (ER) stress-induced apoptosis pathway activation.
1.2K
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
754
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
824
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
373