Resolution of subretinal abscess from presumed Nocardia chorioretinitis with serial intravitreal amikacin

Area of Science:

• Ophthalmology
• Infectious Diseases
• Microbiology

Background:

• Subretinal abscesses caused by Nocardia are uncommon ocular infections.
• Nocardia infections often lead to poor visual prognosis.

Purpose of the Study:

• To report a case of a large submacular Nocardia abscess.
• To evaluate the efficacy of early, frequent intravitreal amikacin and systemic antibiotics.

Main Methods:

• A case study of a patient with a large submacular Nocardia abscess.
• Treatment involved frequent intravitreal injections of amikacin and systemic antibiotic administration.

Main Results:

• The submacular abscess showed a favorable response to the combined treatment.
• Visual outcomes improved following the intervention.

Conclusions:

• Early and frequent intravitreal amikacin, alongside systemic antibiotics, can be an effective treatment for Nocardia subretinal abscess.
• This approach may improve visual outcomes in cases of Nocardia endophthalmitis.