Related Experiment Video
Updated: Jan 20, 2026

A Protocol for Collecting and Constructing Soil Core Lysimeters
Published on: June 6, 2016
Kinematic assessment of an elastic-core cervical disc prosthesis in one and two-level constructs
Richard D Guyer1, Leonard I Voronov2,3, Robert M Havey2,3
1Texas Back Institute Plano Texas.
Introduction:
Anterior cervical discectomy and fusion has been associated with the development of adjacent segment degeneration (ASD), with clinical incidence of approximately 3% per year. Cervical total disc arthroplasty (TDA) has been proposed as an alternative to prevent ASD.
Hypotheses:
TDA in optimal placement using an elastic-core cervical disc (RHINE, K2M Inc., Leesburg, Virginia) will replicate natural kinematics and will improve with optimal vs anterior placement.
Methods:
Seven C3-T1 cervical cadaver spines were tested intact first, then after one-level TDA at C5-C6 anterior placement, after TDA at C5-C6 optimal placement, after two-level TDA at C5-C6 and C6-C7 optimal placement, and finally after two-level TDA at C5-C6 lateral placement and C6-C7 optimal placement. The specimens were subjected to: Flexion-Extension moments (+1.5 Nm) with compressive preloads of 0 N and 150 N, lateral bending (LB) and axial rotation (AR) (+1.5 Nm) without preload.
Results:
C5-C6 TDA in optimal placement resulted in a non-significant increase in flexion-extension ROM compared to intact under 0 N and 150 N preload (P > 0.05). Both LB and AR ROM decreased with arthroplasty (P < 0.01). Optimal placement of C6-C7 TDA resulted in an increase in flexion-extension ROM with preload compared to intact (P < 0.05) while LB and AR ROM decreased with arthroplasty (P < 0.01).
Conclusion:
This six degree of freedom elastic-core disc arthroplasty effectively restored flexion-extension motion to intact levels. In LB the TDA maintained 42% ROM at C5-C6 and 60% at C6-C7. In AR 57% of the ROM was maintained at C5-C6 and 70% at C6-C7. These findings are supported by literature which shows cervical TDA results in restoration of approximately 50% ROM in LB and AR, which is a multifactorial phenomenon encompassing TDA design parameters and anatomical constraints. Anterior placement of this viscoelastic TDA device shows motion restoration similar to optimal placement suggesting its design may be less sensitive to suboptimal placement.
Related Concept Videos
13:23A Protocol for Collecting and Constructing Soil Core Lysimeters
06:11Anterior Cervical Discectomy and Fusion in the Ovine Model
11:16Engineering Platform and Experimental Protocol for Design and Evaluation of a Neurally-controlled Powered Transfemoral Prosthesis
The Nucleosome Core Particle
The paradox
Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...
10:193D Kinematic Gait Analysis for Preclinical Studies in Rodents
Kinematics and Projectile Motion
This experiment demonstrates the kinematics of motion in 1 and 2 dimensions. This lab will begin by studying motion in 1 dimension, under constant acceleration, by launching a projectile directly upward and measuring the maximum height reached. This lab will verify that the maximum height reached is consistent with the kinematic...

