Erratum: New horizons in spine research: Disc biology, tissue engineering, biomechanics, translational, and clinical...

This article outlines a versatile method to create cell-derived tissue rings by cellular self-assembly. Smooth muscle cells seeded into ring-shaped agarose wells aggregate and contract to form robust three-dimensional (3D) tissues within 7 days. Millimeter-scale tissue rings are conducive to mechanical testing and serve as building blocks for tissue...

We developed a lumbar intervertebral disc degeneration mouse model by resection of L3–L5 spinous processes along with supra- and inter-spinous ligaments and detachment of paraspinous...

We present a model of ligament tissue in which three-dimensional constructs are treated with the human exercise-conditioned serum and analyzed for collagen content, function, and cellular...

Tissue engineering aims to create artificial tissue from biomaterials, specific cells, and growth factors. These engineered tissue constructs have far-reaching benefits, with possibilities for organ replacement and tissue repair.
This video introduces the field of tissue engineering and examines the components of engineered tissue. This video also outlines some prominent methods used to create the tissue scaffold, introduce a cell population, and encourage growth and proliferation.