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Updated: Jan 20, 2026

A Paper-Based Immunoassay for the Detection of Immunoglobulin G
Atom transfer radical polymer-modified paper for improvement in protein fixation in paper-based ELISA
Lu Qi1, Aihong Zhang2, Yu Wang1
11Phase I Clinical Trial Center, Beijing Shijitan Hospital, Capital Medical University, Beijing, 100038 China.
Abstract:
A newly modified paper-based enzyme-linked immunosorbent assay (P-ELISA) was established by immobilizing more proteins on the paper surface through an atom transfer radical polymerization (ATRP) reaction. In addition, introducing graphene oxide (GO) sheets, Au nanoparticles (AuNps) and two primary antibodies (Ab1s) led to signal amplification and cost reduction.
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