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Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro
Published on: June 13, 2011
Episodic and chronic migraine in children
Paul E Youssef1, Kenneth J Mack1
1Department of Neurology, Division of Child and Adolescent Neurology, Mayo Clinic, Rochester, MN, USA.
Insights
Pediatric migraine, a common headache in children, presents uniquely and impacts quality of life. This review details clinical features and treatment options for childhood migraine, including chronic forms.
Area of Science:
- Pediatric Neurology
- Headache Medicine
Background:
- Migraine is the most frequent acute, recurrent headache syndrome in children.
- Pediatric migraine exhibits distinct clinical features that can change with age.
- This condition significantly affects a child's quality of life, impacting education and social interactions.
Purpose of the Study:
- To review the diverse clinical presentations of migraine in children.
- To discuss current and emerging treatment strategies for pediatric migraine.
- To address management of chronic migraine in pediatric populations.
Main Methods:
- Literature review of pediatric migraine.
- Analysis of clinical characteristics and phenotypes.
- Synthesis of treatment options for acute and chronic migraine.
Main Results:
- Migraine in children presents with varied phenotypes, which may evolve over time.
- A comprehensive, multifaceted approach is often required for effective headache management.
- Expanded treatment options are available for chronic migraine in children.
Conclusions:
- Understanding the unique aspects of pediatric migraine is crucial for diagnosis and management.
- Multifaceted treatment plans, including lifestyle adjustments and pharmacotherapy, are key.
- Effective management strategies can improve outcomes for children with chronic migraine.
Abstract:
Migraine is the most common acute and recurrent headache syndrome in children. This condition has unique clinical characteristics in the pediatric population, that can evolve with age, and significantly impact a child's quality of life, affecting their education, socialization, and family life. The purpose of this review is to describe the varied clinical features of migraine seen in children, and discuss potential treatment options for pediatric migraine, including chronic migraine. In many patients a multifaceted approach involving lifestyle changes, treatment of comorbid conditions, and pharmacological treatments are needed for optimal headache control. WHAT THIS PAPER ADDS: Migraine presents as various phenotypes in children, sometimes evolving as the child ages. An expanded range of treatment options exists for the challenging chronic migraine patient.
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