G-Spot Anatomy and its Clinical Significance: A Systematic Review.

Area of Science:

• Anatomy
• Histology
• Sexual Medicine

Background:

• The G-spot was previously defined as a physiological phenomenon without a clear anatomical basis.
• Lack of systematic reviews hindered understanding of its anatomical existence.
• Previous definitions were insufficient as physiological responses require anatomical correlates.

Purpose of the Study:

• To determine if current scientific and clinical data are sufficient to resolve the G-spot anatomical existence controversy.
• To provide evidence-based information on the G-spot through a systematic review.
• To explore the G-spot's anatomical and histological characteristics.

Main Methods:

• Systematic review of postmortem and in vivo studies from 1950 to May 2019.
• Searches conducted using manual and electronic methods.
• Articles quality-assessed using validated instruments and PRISMA-IPD guidelines.

Main Results:

• Identified reliable scientific-clinical data supporting an anatomical G-spot structure.
• Observed transient anterior-distal vaginal wall engorgement due to blood entrapment in the G-spot.
• Histological examination ruled out the G-spot as the source of female ejaculation due to lack of glandular tissue.

Conclusions:

• The G-spot has a demonstrable anatomical structure.
• Findings may aid in developing treatments for secondary G-spot dysfunction.
• Further scientific and clinical research is warranted to advance understanding and potential interventions.