Related Experiment Video

Updated: Jan 20, 2026

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis
04:36

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis

Published on: October 2, 2020

2.6K

Correlation between central arterial stiffness and handgrip strength in chronic hemodialysis patients

Cut Mela Yunita Sari1, 1, Ginova Nainggolan1

  • 1Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia and Dr. Cipto Mangunkusumo General National Hospital, Jakarta, Indonesia.

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
|August 30, 2019
PubMed

Insights

Central arterial stiffness showed no overall correlation with handgrip strength (HGS) in chronic hemodialysis patients. However, a subgroup of women with height over 150 cm exhibited a moderate negative correlation, suggesting potential links in specific populations.

Area of Science:

  • Cardiovascular Physiology
  • Nephrology
  • Gerontology

Background:

  • Central arterial stiffness is a marker of cardiovascular risk.
  • Handgrip strength (HGS) reflects overall muscle strength and health.
  • The relationship between arterial stiffness and HGS in hemodialysis patients is not well-established.

Purpose of the Study:

  • To investigate the correlation between central arterial stiffness and HGS in patients undergoing chronic hemodialysis.
  • To explore potential confounding factors influencing this relationship.

Main Methods:

  • A cross-sectional study was conducted with 85 hemodialysis patients (18-60 years).
  • Central arterial stiffness was measured using SphygmoCor® (central pulse wave velocity, cPWV).
  • Handgrip strength (HGS) was assessed using a Jamar® dynamometer. Data were analyzed using bivariate and partial correlation.

Main Results:

  • No statistically significant correlation was found between cPWV and HGS in men (r = -0.046, P = 0.763) or women (r = -0.285, P = 0.113).
  • A moderate negative correlation between cPWV and HGS was observed in women over 150 cm tall (r = -0.466, P = 0.016), with cPWV explaining 21.7% of HGS variance.
  • Low HGS was associated with increased cPWV across all age categories.

Conclusions:

  • Central arterial stiffness is not generally associated with HGS in chronic hemodialysis patients.
  • A specific subgroup of women may show a correlation, warranting further investigation.
  • Confounding factors significantly influence the relationship between cPWV and HGS.

More Related Videos

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness05:51

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Published on: May 3, 2018

18.4K
Assessment of Vascular Function in Patients With Chronic Kidney Disease08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

16.7K

Related Concept Videos

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis04:36

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis

We present a protocol to measure regional oxygen saturation (rSO2) in hemodialysis (HD) patients by using a near-infrared spectroscopy monitor. The rSO2 value is an index of tissue oxygenation. This noninvasive and real-time monitoring could be useful for confirming changes in organ oxygenation during...
2.6K
Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness05:51

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness

This protocol describes a method to standardize the measurements of carotid-femoral pulse wave velocity to evaluate arterial...
18.4K
Assessment of Vascular Function in Patients With Chronic Kidney Disease08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

The degree of vascular dysfunction and contributing physiological mechanisms can be assessed in patients with chronic kidney disease by measuring brachial artery flow-mediated dilation, aortic pulse-wave velocity, and vascular endothelial cell protein...
16.7K
A Murine Model of Hemodialysis Access-Related Hand Dysfunction08:39

A Murine Model of Hemodialysis Access-Related Hand Dysfunction

This protocol details the surgical steps of murine common iliac arteriovenous fistula creation. We developed this model to study hemodialysis access-related limb pathophysiology.
2.0K
Manual Muscle Testing: A Method of Measuring Extremity Muscle Strength Applied to Critically Ill Patients09:44

Manual Muscle Testing: A Method of Measuring Extremity Muscle Strength Applied to Critically Ill Patients

Survivors of acute respiratory distress syndrome (ARDS) and critical illness frequently develop long-lasting muscle weakness. Manual muscle testing (MMT) is a standardized clinical examination commonly used to measure strength of peripheral skeletal muscle groups. This video demonstrates MMT using the 6-point Medical Research Council...
83.0K
Correlations02:20

Correlations

Correlation means that there is a relationship between two or more variables (such as ice cream consumption and crime), but this relationship does not necessarily imply cause and effect. When two variables are correlated, it simply means that as one variable changes, so does the other. We can measure correlation by calculating a statistic known as a correlation coefficient. A correlation coefficient is a number from -1 to +1 that indicates the strength and direction of the relationship between...
35.8K