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Updated: Jan 20, 2026

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
Published on: February 28, 2013
[Depressive disorders and diabetes mellitus in children and adolescents]
Yu F Antropov1, E A Korabelnikova2, I A Makarova3
1FSDEI AVE Russian Medical Academy of Continuing Professional Education, Moscow, Russia.
Aim:
To clarify the role of depressive disorders and personality traits in the pathogenesis of diabetes mellitus type I in children and adolescents.
Material And Methods:
One hundred and three patients with diabetes, aged from one year nine months to 17 years, mean 9.7±0.7), with diabetes mellitus and depressive disorders were studied using clinical-psychopathological, psychometric, paraclinical and statistical methods.
Results:
Biological and psychosocial risk factors of a somatic disorder have been identified. Mental disorders are represented by affective disorders and personality features of the patients. Affective disorders include mild psychogenic anxiety and asthenic-anxiety depression, personality features are represented by hysterical signs and emotional lability. Clinical variants of these mental disorders and their diagnostic assessment according to ICD-10 are presented.
Conclusion:
The dynamics of diabetes mellitus correlate with characteristics of depressive disorders. This result can be used to optimize the therapy of diabetes mellitus.
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