Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging06:08

Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging

17.2K
We demonstrated that malignant pigmented lesions with increased metabolic activity generate quantifiable amounts of heat and the measurement of the transient thermal response of the skin to a cooling excitation allows quantitative identification of melanoma and other skin cancers (vs. non-proliferative nevi) at an early stage of the disease.
17.2K
Skin Cancer01:30

Skin Cancer

5.7K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.7K
Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology08:27

Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology

15.3K
Intact class I HLA/peptide complexes are shed by cancer cells, representing a potential relevant cancer biomarker. Utilizing label-free sensor technology and T-cell receptor mimicking monoclonal antibodies, detection of shed MIF/HLA-A*02:01 complexes in MDA-MB-231 cell supernatants, spiked human serum, and patient plasma is demonstrated, enabling development of a novel cancer diagnostic...
15.3K
Chemical-induced Two-stage Skin Carcinogenesis Model: An Experimental In Vivo Mouse Model of Skin Cancer03:02

Chemical-induced Two-stage Skin Carcinogenesis Model: An Experimental In Vivo Mouse Model of Skin Cancer

2.2K
This video describes the procedure to induce two-stage skin carcinogenesis to study tumor initiation by topical application of chemicals. In the first step, a mutagen, DMBA, is applied onto the skin of a mouse model which initiates tumor formation by causing mutations in the stem cells, followed by the application of a growth stimulator, TPA, which accelerates skin papilloma...
2.2K
Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

2.9K
Here, we describe protocols for acquiring good-quality images using novel, noninvasive imaging devices of reflectance confocal microscopy (RCM) and combined RCM and optical coherence tomography (OCT). We also familiarize clinicians with their clinical applications so that they can integrate the techniques into regular clinical workflows to improve patient...
2.9K
Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing05:17

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

354
This protocol describes an automated, ISO15189-accredited next-generation sequencing workflow for detecting targetable genomic alterations in non-small cell lung cancer (NSCLC) formalin-fixed paraffin-embedded...
354

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Outcomes of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Based on Hospital Admission Type.

Cutis·2025
Same author

Lower oncogenic risk with dermatologic use of mycophenolate mofetil compared with transplant prophylaxis: A retrospective study.

Journal of the American Academy of Dermatology·2025
Same author

Management of Mycosis Fungoides and Sézary Syndrome With Oral Systemic Therapies.

Journal of cutaneous medicine and surgery·2025
Same author

Implementation of the atopic dermatitis yardstick via the electronic medical record: a pilot study to improve clinical documentation and patient education.

Dermatology online journal·2024
Same author

Outcomes in an educational skin-model session on point-of-care ultrasound for diagnosing calciphylaxis.

Skin health and disease·2024
Same author

Mycophenolate mofetil as a steroid-sparing agent in oral mucous membrane pemphigoid: A retrospective review.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024

Related Experiment Video

Updated: Jan 20, 2026

Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging
06:08

Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging

Published on: May 5, 2011

17.2K

Skin Cancer Detection Technology.

Deborah N Dorrell1, Lindsay C Strowd2

  • 1Wake Forest School of Medicine, Medical Center Blvd, Winston-Salem, NC 27103, USA.

Dermatologic Clinics
|August 31, 2019
PubMed
Summary

This review covers new noninvasive skin cancer detection technologies that aim to improve early diagnosis. While promising, these methods face challenges with cost, training, and specificity compared to traditional biopsy.

Keywords:
MelanomaMultispectral digital skin lesion analysisNonmelanoma skin cancerOptical coherence tomographyPigmented lesion assayReflectance confocal microscopySkin cancer

More Related Videos

Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology
08:27

Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology

Published on: March 24, 2015

15.3K
Skin Cancer
01:30

Skin Cancer

5.7K

Related Experiment Videos

Last Updated: Jan 20, 2026

Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging
06:08

Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging

Published on: May 5, 2011

17.2K
Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology
08:27

Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology

Published on: March 24, 2015

15.3K
Skin Cancer
01:30

Skin Cancer

5.7K

Area of Science:

  • Dermatology and oncology
  • Medical imaging and diagnostics

Background:

  • Skin cancer is the most common malignancy in the United States.
  • Early detection of suspicious skin lesions is crucial for timely treatment.
  • Traditional diagnosis involves visual inspection, dermoscopy, biopsy, and histopathology.

Purpose of the Study:

  • To review innovative, noninvasive skin cancer detection technologies.
  • To discuss the benefits and limitations of these emerging techniques.
  • To provide an overview of current advancements in skin cancer diagnostics.

Main Methods:

  • Literature review of recent studies on skin cancer detection technologies.
  • Analysis of noninvasive diagnostic tools and their performance.
  • Comparison of novel techniques with standard biopsy and histopathology.

Main Results:

  • Several innovative noninvasive technologies for skin cancer detection have been developed.
  • These technologies offer potential advantages over traditional biopsy methods.
  • Current limitations include high cost, required specialized training, and insufficient specificity.

Conclusions:

  • Noninvasive technologies represent a significant advancement in skin cancer detection.
  • Further research and development are needed to overcome current limitations.
  • Optimizing these tools could enhance diagnostic accuracy and patient outcomes.