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Updated: Jan 20, 2026

Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome
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Identification of Novel Fusion Transcripts in Undifferentiated Pleomorphic Sarcomas by Transcriptome Sequencing

Biqiang Zheng1,2, Shuirong Zhang3, Weiluo Cai1,2

  • 1Department of Musculoskeletal Cancer Surgery, Fudan University Shanghai Cancer Center, Shanghai, P.R. China.

Cancer Genomics & Proteomics
|August 31, 2019
PubMed
Abstract

Keywords:
RB1Soft tissue sarcomafusion genepseudogenetargetable fusiontranscriptome sequencingundifferentiated pleomorphic sarcoma

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Nuclear Fusion

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Transcription01:10

Transcription

Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
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