A comparative study between haemocoagulase and adrenaline in type 1 tympanoplasty

Area of Science:

• Otolaryngology
• Surgical Hemostasis
• Pharmacology

Background:

• Achieving hemostasis is crucial in ear surgeries.
• Topical methods like manual pressure, adrenaline, and hemostatic agents are common.
• The efficacy of different agents requires comparative study.

Purpose of the Study:

• To compare the efficacy of haemocoagulase and adrenaline for middle ear hemostasis in type 1 tympanoplasty.
• To evaluate the effect of haemocoagulase on the middle ear.

Main Methods:

• Prospective comparative study of 100 patients undergoing type 1 tympanoplasty.
• Group A: 50 patients received haemocoagulase-soaked cotton balls.
• Group B: 50 patients received adrenaline (1:1000)-soaked cotton balls.

Main Results:

• Adrenaline required fewer cotton balls and resulted in shorter surgery duration for congested mucosa.
• The adrenaline group showed significantly higher mean blood pressure.
• No significant difference in postoperative hearing improvement was observed between groups.

Conclusions:

• Adrenaline is more effective for middle ear hemostasis than haemocoagulase.
• Haemocoagulase presents a safe option for patients with hypertension.