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Updated: Jan 20, 2026
Ozonolysis of Alkenes: Principle and Applications
Published on: April 30, 2023
Vicinal difunctionalization of alkenes by four-component radical cascade reaction of xanthogenates, alkenes, CO, and
Shuhei Sumino1, Takahide Fukuyama1, Mika Sasano1
1Department of Chemistry, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan.
Abstract:
Four-component coupling reactions between xanthogenates, alkenes, CO, and sulfonyl oxime ethers were studied. In the presence of hexabutylditin, working as a propagating radical reagent, the chain reaction proceeds, as expected, taking into account reagents polarities, affording the corresponding functionalized α-keto oximes. Although yields are modest, this rare one-pot four-component process is easy to carry out and the resulting compounds, bearing multiple functionalities, have the potential for further elaboration.
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