Long Term Follow-up of an Open Bicondylar Hoffa Fracture with a Disrupted Extensor Mechanism: A Case Report

Quantification of knee extensor maximal strength is imperative to understand functional adaptations to aging, disease, injury, and rehabilitation. We present a novel method to repeatedly measure in vivo knee extension isometric peak tetanic...

Source: Taylor, M. N. et al. Using Single-Worm Data to Quantify Heterogeneity in Caenorhabditis elegans-Bacterial Interactions. J. Vis. Exp. (2022)This video demonstrates the quantification of intestinal bacterial load variability in individual Caenorhabditis elegans through mechanical disruption. It outlines the steps for sample preparation, mechanical disruption, serial dilution, and colony counting to assess differences in intestinal bacterial load among individual...

The goal of the protocol is to optimize the fracture generation parameters to yield consistent fractures. This protocol accounts for the variations in bone size and morphology that may exist between animals. Additionally, a cost-effective, adjustable fracture apparatus is...

This protocol presents a comprehensive and efficient method for analyzing mandibular bone repair. We describe a reproducible technique for non-stabilized mandibular fracture in a mouse model, allowing analysis of the process of endochondral bone repair with minimal tissue damage and bone loss.

Personalized medicine for orbital reconstruction is developing rapidly. Due to the delicate nature of the orbit, small discrepancies following fracture reconstruction may cause impairment in visual perception. Here, we describe three methods for virtual 3D reconstruction of orbital defects and their indications and potential pitfalls for correct reconstruction.

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.