Dermoscopic findings in neonatal leukemia cutis

Area of Science:

• Dermatology
• Pediatric Oncology
• Hematology

Background:

• Leukemia cutis is the infiltration of leukemic cells into the skin.
• It can manifest in neonates, sometimes presenting as the 'blueberry muffin baby' phenotype.
• Early diagnosis is crucial for appropriate management.

Observation:

• A case of neonatal leukemia cutis was analyzed.
• Dermoscopic examination of the cutaneous lesions was performed.
• Specific vascular patterns were noted within the lesions.

Findings:

• The lesions exhibited a pink background.
• Fine telangiectatic arborizing vessels were consistently observed within all lesions.
• These dermoscopic features are characteristic of leukemia cutis in neonates.

Implications:

• Dermoscopy can be a valuable non-invasive tool for diagnosing neonatal leukemia cutis.
• Recognizing these dermoscopic features can expedite diagnosis and treatment initiation.
• This finding contributes to the understanding of the clinical and dermoscopic spectrum of neonatal leukemic infiltration.