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Related Concept Videos

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase07:27

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The fate of the replisome following a collision with a head-on RNA polymerase (RNAP) is unknown. We find that the replisome stalls upon collision with a head-on RNAP, but resumes elongation after displacing the RNAP from DNA. Mfd promotes replication restart by facilitating displacement of the RNAP after the...
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Targeted cross-linking mass spectrometry creates quaternary protein structure models using mass spectrometry data acquired using up to three different acquisition protocols. When executed as a simplified workflow on the Cheetah-MS web server, the results are reported in a Jupyter Notebook. Here, we demonstrate the technical aspects of how the Jupyter Notebook can be extended for a more in-depth...
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This article describes an experimental protocol using electrospray-ion mobility-mass spectrometry, semi-empirical quantum calculations, and energy-resolved threshold collision-induced dissociation to measure the relative thermochemistry of the dissociation of related ternary metal...
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The application of high-frequency low-energetic stimulation can alleviate the symptoms of gastric dysmotility. In this research, a miniature, endoscopically implantable and wirelessly rechargeable device which is implanted into a submucosal pocket is presented. Successful both-way communication and stimulation control were achieved during an experiment on live...
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Related Experiment Video

Updated: Jan 20, 2026

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
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Reply

Alexis Mathian1, Suzanne Mouries-Martin1, Karim Dorgham1

  • 1Sorbonne Université, AP-HP Hôpital Pitié-SalpêtrièreFrench National Referral Center for SystemicLupus Erythematosus, Antiphospholipid AntibodySyndrome and Other Autoimmune DisordersService de Médecine Interne 2, Institut E3MINSERM UMRS, CIMI-Paris, Paris, France.

Arthritis & Rheumatology (Hoboken, N.J.)
|August 31, 2019
PubMed
Summary

No abstract available in PubMed .

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