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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential07:11

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The isolated-check visual evoked potential (icVEP) method is implemented here to assess the magnocellular ON pathway that is initially damaged in glaucoma. The study shows standard operative procedures using icVEP to obtain reliable results. It is proved to serve as a useful objective diagnosing technology for the early detection of...
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Experimental Glaucoma Induction via Iridocorneal Angle Obstruction In a Mouse Model03:04

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In this video, an anesthetized rat undergoes an ocular procedure where magnetic beads are injected into the anterior chamber under a magnetic field to block the iridocorneal angle. This blockage obstructs the trabecular meshwork, preventing aqueous humor drainage and leading to increased intraocular pressure, damaging the retinal ganglion cells and optic nerve. This develops a glaucoma-like...
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Force and Position Control in Humans - The Role of Augmented Feedback06:31

Force and Position Control in Humans - The Role of Augmented Feedback

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Controlling an identical movement with position or force feedback results in different neural activation and motor behavior. This protocol describes how to investigate behavioral changes by looking at neuromuscular fatigue and how to evaluate motor cortical (inhibitory) activity using subthreshold TMS with respect to the interpretation of augmented feedback.
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We present a protocol to isolate primary adult fibroblasts in an easy, fast and reliable way, performable by beginners (e.g., students). The procedure combines enzymatic tissue digestion and mechanical agitation with ultrasonic waves to obtain primary fibroblasts. The protocol can easily be adapted to specific experimental requirements (e.g., human...
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Related Experiment Video

Updated: Jan 20, 2026

Angle Closure Glaucoma: Treatment
01:28

Angle Closure Glaucoma: Treatment

1.2K

Mitomycin C-augmented Phacotrabeculectomy Versus Phacoemulsification in Primary Angle-closure Glaucoma: A Randomized

Yasmine M El Sayed1, Abdelrahman M Elhusseiny, Ahmed S Albalkini

  • 1Department of Ophthalmology, Kasr Al-Ainy School of Medicine, Cairo University, Cairo, Egypt.

Journal of Glaucoma
|August 31, 2019
PubMed
Summary
This summary is machine-generated.

Phacotrabeculectomy and phacoemulsification show similar results for primary angle-closure glaucoma (PACG) regarding intraocular pressure (IOP) and success rates. However, phacotrabeculectomy had more complications and interventions, despite releasable sutures.

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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
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Open Angle Glaucoma: Treatment
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Angle Closure Glaucoma: Treatment
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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

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Open Angle Glaucoma: Treatment
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Area of Science:

  • Ophthalmology
  • Glaucoma Surgery
  • Surgical Techniques

Background:

  • Primary angle-closure glaucoma (PACG) management requires effective surgical interventions.
  • Comparing combined procedures with standalone techniques is crucial for optimizing patient outcomes.

Purpose of the Study:

  • To compare the efficacy and safety of mitomycin C-augmented phacotrabeculectomy with releasable sutures versus phacoemulsification alone in PACG patients.

Main Methods:

  • A randomized study involving 63 PACG patients.
  • Surgical groups: mitomycin C-augmented phacotrabeculectomy with releasable sutures vs. phacoemulsification alone.
  • Outcomes assessed: intraocular pressure (IOP), glaucoma medications, success rates, and complications.

Main Results:

  • Both procedures significantly reduced IOP and medication use.
  • No significant difference in IOP, success rates, or survival between groups.
  • Phacotrabeculectomy group had higher rates of complications and postoperative interventions.
  • Complete success rates were comparable (58% vs. 62%).

Conclusions:

  • Phacotrabeculectomy does not offer an advantage over phacoemulsification alone for PACG.
  • The combined procedure was associated with increased postoperative complications and interventions.
  • Releasable sutures did not mitigate the higher complication rate in the phacotrabeculectomy group.