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Related Experiment Video

Updated: Jan 20, 2026

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke

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Published on: June 6, 2025

A gate-keeping test for selecting adaptive interventions under general designs of sequential multiple assignment

Xiaobo Zhong¹, Bin Cheng², Min Qian²

¹Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Biostatistics, Columbia University, New York, NY, USA.

Contemporary Clinical Trials

|August 31, 2019

Summary

This study introduces a new statistical method to improve power in sequential multiple assignment randomized trials (SMART) by simultaneously comparing all adaptive interventions. This approach enhances the selection of the most effective treatment strategies.

Failed At:

2026-06-19T13:38:21.632322+00:00

Keywords:

Adaptive intervention Gate-keeping approach Omnibus test Sample size calculation Sequential multiple assignment randomized trial

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