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Updated: Aug 10, 2026

05:22
Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
Looking for gall bladder disease in the patient's iris
1Department of Epidemiology and Health Care Research, University of Limburg, Maastricht, The Netherlands.
Summary
Iridology, an alternative diagnostic method, was evaluated for diagnosing gall bladder disease. The study found iridology
Area of Science:
- Alternative medicine
- Ophthalmology
- Diagnostic methods
Background:
- Iridology is utilized in alternative healthcare as a diagnostic tool.
- Specific iris signs are believed to indicate gall bladder disease, including inflammation and gallstones.
Purpose of the Study:
- To assess the diagnostic validity of iridology for gall bladder disease.
- To evaluate the inter-performer consistency among iridologists in diagnosing this condition.
Main Methods:
- Stereo color slides of the right eye were collected from 39 patients with gall bladder disease and 39 age- and sex-matched controls.
- Five leading iridologists assessed the slides in random order, without additional patient information.
Main Results:
- The estimated prevalence of gall bladder disease was 56%.
- Median validity was 51% (sensitivity 54%, specificity 52%), which is comparable to chance.
- Inter-performer consistency was moderate at 60%, also only slightly better than chance.
Conclusions:
- Iridology demonstrated low diagnostic validity and only slightly better-than-chance consistency among practitioners.
- The findings suggest iridology is not a reliable diagnostic aid for gall bladder disease.
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