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Updated: Jan 20, 2026
Establishment and Histological Analysis of Esophageal Organoids Modeling the Progression from Normal to Cancerous Tissues
Published on: May 30, 2025
Genetic and molecular bases of esophageal Cancer among Iranians: an update
Mohammad Reza Abbaszadegan1, Vahideh Keyvani2, Meysam Moghbeli3
1Medical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Background:
Esophageal cancer is one of the leading causes of cancer related deaths among the Iranians. There is still a high ratio of mortality and low 5 years survival which are related to the late onset and diagnosis. Majority of patients refer for the treatment in advanced stages of tumor progression.
Main Body:
It is required to define an efficient local panel of diagnostic and prognostic markers for the Iranians. Indeed such efficient specific panel of markers will pave the way to decrease the mortality rate and increase the 5 years survival among the Iranian patients via the early diagnosis and targeted therapy.
Conclusion:
in present review we have reported all of the molecular markers in different signaling pathways and cellular processes which have been assessed among the Iranian esophageal cancer patients until now.
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