Related Experiment Video
Updated: Jan 20, 2026

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
Choroidal juxtapapillary neovascularization regression in multiple evanescent white dot syndrome by optical coherence
Maria Cristina Savastano1, Marco Rispoli2, Bruno Lumbroso2
1Centro Italiano Macula, Via Angelo Brofferio, 7, 00196, Rome, Italy. mariacristina.savastano@gmail.com.
Background:
Multiple evanescent white dot syndrome most often resolves spontaneously without complications; however, choroidal neovascularization can sometimes occur.
Case Presentation:
Here, we describe a case of a 22-year-old white Caucasian man with blurred vision in his left eye who exhibited juxtapapillary choroidal neovascularization on optical coherence tomography angiography. Although multiple evanescent white dot syndrome is often self-limiting, to reduce the possibility of an inflammatory reaction, we preferred to administer prednisolone orally. After 3 months, significant regression of juxtapapillary neovascularization was observed by B-scan and optical coherence tomography angiography. Symptoms resolved in 3 months. A steady situation was observed at 4 years of follow-up.
Conclusion:
This case report highlights the helpful use of optical coherence tomography angiography in daily clinical practice, even in inflammatory diseases, such as atypical juxtapapillary neovascularization in multiple evanescent white dot syndrome. Choroidal neovascularization associated with multiple evanescent white dot syndrome by means of optical coherence tomography angiography showed neovascular activity regression, thus avoiding invasive therapy.
Related Concept Videos
09:56In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
07:08A Mouse Model for Laser-induced Choroidal Neovascularization
05:46Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
09:20Novel Photoacoustic Microscopy and Optical Coherence Tomography Dual-modality Chorioretinal Imaging in Living Rabbit Eyes
11:21Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
08:22Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

