Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System

This article describes the process used by Örebro University Hospital to produce double dose buffy coat platelet concentrates prepared from whole blood donations and treated with the INTERCEPT Blood System for pathogen inactivation. The in vitro quality of the final platelet units are evaluated over 7 days of...

A Simple Double Centrifugation Tube Method to Obtain Platelet-rich Plasma from Equine Blood

A Simple Double Centrifugation Tube Method to Obtain Platelet-rich Plasma from Equine Blood

Platelet-rich plasma (PRP) is used in the treatment of equine musculoskeletal disorders. Different techniques yield PRP with varying platelet and leukocyte concentrations. This article describes a method for obtaining PRP from horse...

Purification of Platelets from Mouse Blood

Purification of Platelets from Mouse Blood

Here, mouse blood was collected in the presence of an anti-coagulant. The platelets were purified by iohexol gradient medium using low speed centrifugation. The platelets were activated with thrombin to investigate if they were viable. The quality of the purified platelets was analyzed by flow cytometry and...

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro

Platelet transfusion and hemostasis was modeled using blood reconstitution and microfluidic flow chambers to investigate the function of blood banking platelets. The data demonstrate the consequences of platelet storage lesion on hemostasis, in vitro.

Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation

Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation

We describe a straightforward method for the isolation of washed platelets from human blood followed by agonist-induced platelet aggregation measurements by turbidimetry. As an example we apply this method for studying the aggregation response of human platelets to collagen after a pre-incubation with the Pannexin1 channel inhibitor Brilliant Blue...

Preparation of Platelet-Rich Plasma from Human Peripheral Blood

Preparation of Platelet-Rich Plasma from Human Peripheral Blood

Source:Sathish Muthu1,2,31Orthopaedic Research Group, Coimbatore.2Department of Biotechnology, Faculty of Engineering, Karpagam Academy of Higher Education.3Department of Orthopaedics, Government Medical College.This video demonstrates the preparation of high-quality Platelet-Rich Plasma (PRP) by screening for platelet count, collecting and centrifuging blood, and isolating platelets. This PRP is used in therapeutic applications for tissue regeneration and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effect of Sevelamer and B. longum on Insulin Sensitivity in Participants With Obesity: A Randomized Clinical Trial.

Obesity (Silver Spring, Md.)·2026

Same author

When resources run short: the inhibitory effect of economic scarcity on third-party punishment.

Frontiers in psychology·2026

Same author

Disconnected emotions, connected behaviors: Symptom network features of problematic mobile phone use across different alexithymia profiles.

Addictive behaviors·2025

Same author

Problematic mobile phone use and Shyness: A network perspective on User differences.

Addictive behaviors·2025

Same author

Detectability Driven Recommendation of Anomaly Detection Models for Time-Series Data.

IEEE transactions on cybernetics·2025

Same author

Effect of Sevelamer versus <i>Bifidobacterium longum</i> on Insulin Sensitivity in Subjects with Obesity.

medRxiv : the preprint server for health sciences·2025

Search research articles

Related Experiment Video

Updated: Jan 20, 2026

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System

Published on: December 7, 2012

Giant Platelets Induce Double Interference in Complete Blood Count.

Lin Wang^1,2, Hong Wang^1,2, Hanyu Liang^1,2

¹Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University and.

Annals of Clinical and Laboratory Science

|September 1, 2019

Summary

This summary is machine-generated.

Giant platelets can interfere with automated blood counts, causing falsely low platelet counts and falsely high white blood cell counts. Manual dilution methods are crucial for accurate results in such rare cases.

Area of Science:

Hematology
Clinical Pathology
Laboratory Medicine

Background:

Automated cell counters are standard for blood analysis.
Certain conditions, like giant platelets, can cause analytical interferences.

More Related Videos

A Simple Double Centrifugation Tube Method to Obtain Platelet-rich Plasma from Equine Blood

A Simple Double Centrifugation Tube Method to Obtain Platelet-rich Plasma from Equine Blood

Published on: August 15, 2025

Purification of Platelets from Mouse Blood

Purification of Platelets from Mouse Blood

Published on: May 7, 2019

Related Experiment Videos

Last Updated: Jan 20, 2026

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System

Published on: December 7, 2012

A Simple Double Centrifugation Tube Method to Obtain Platelet-rich Plasma from Equine Blood

A Simple Double Centrifugation Tube Method to Obtain Platelet-rich Plasma from Equine Blood

Published on: August 15, 2025

Purification of Platelets from Mouse Blood

Purification of Platelets from Mouse Blood

Published on: May 7, 2019

Accurate blood cell counts are vital for patient diagnosis and management.