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Updated: Jan 20, 2026
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
Published on: June 7, 2015
Radiation Therapy for Uterine Cervical Cancer With Lung Metastases Including Oligometastases
Yuki Mukai1, Izumi Koike2, Tatsuya Matsunaga3
1Department of Radiation Oncology, Yokohama City University Graduate School of Medicine, Yokohama, Japan y_mukai@yokohama-cu.ac.jp.
Background/Aim:
To investigate the role and outcomes of radiation therapy (RT) for stage IVB uterine cervical cancer (UCC) patients with lung (oligo) metastases due to the lack of recent reports on the subject.
Patients And Methods:
The cohort for this retrospective study comprised 23 consecutive patients with UCC (squamous cell carcinoma, n=13) and lung metastases who had received pelvic RT. Ten had lung metastases only, including 7 with oligometastases (≤4 lung metastases); the remaining 13 also had other distant metastases.
Results:
Nine (39.1%) of the 22 patients (95.7%) completed RT without interruption. The 1-year primary progression-free rate was 95.2%. The 1-year overall survival rate was 47.2 % (estimated median survival: 9 months). Significant prognostic factors for survival included: i) ≤4 lung metastases (p=0.035), ii) unilateral lung metastases (p=0.039), iii) primary tumor diameter <100 mm (p<0.001), and iv) ECOG performance status <1 (p=0.015).
Conclusion:
RT is safe and effective for stage IVB UCC patients with lung metastases.
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