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Source: Schregel, K., et al. Optimized Management of Endovascular Treatment for Acute Ischemic Stroke. J. Vis. Exp. (2018).This video demonstrates the endovascular treatment of acute ischemic stroke using the stent retriever-assisted vacuum-locked extraction technique. A guiding sheath is introduced through the femoral artery to reach the clot. A catheter with a stent retriever secures and extracts the clot. Vascular imaging is done to confirm successful...
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Related Experiment Video

Updated: Jan 20, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
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Endovascular Thrombectomy for Acute Ischemic Stroke.

Tasneem F Hasan1, Nathaniel Todnem2, Neethu Gopal3

  • 1Department of Neurology, Ochsner Louisiana State University Health Sciences Center, Shreveport, LA, USA.

Current Cardiology Reports
|September 1, 2019
PubMed
Summary

Endovascular thrombectomy (EVT) is now standard care for acute ischemic stroke (AIS) from large vessel occlusion (LVO) up to 24 hours. Advanced imaging guides treatment beyond traditional time limits, improving patient outcomes.

Keywords:
Acute ischemic strokeDAWNDEFUSE 3EndovascularStent retrieversThrombectomy

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Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research
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Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research
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Area of Science:

  • Neurology
  • Interventional Cardiology
  • Radiology

Background:

  • Acute ischemic stroke (AIS) management has evolved significantly.
  • Endovascular thrombectomy (EVT) has emerged as a critical treatment for large vessel occlusion (LVO).

Purpose of the Study:

  • To review current evidence supporting EVT for AIS due to anterior circulation LVO.
  • To highlight advancements in EVT patient selection and treatment windows.

Main Methods:

  • Review of recent clinical trials and guidelines.
  • Analysis of evidence for extended therapeutic windows in AIS treatment.

Main Results:

  • EVT significantly reduces morbidity and mortality in selected AIS patients with LVO.
  • DAWN and DEFUSE-3 trials extended EVT eligibility to 24 hours based on imaging and clinical findings.
  • EVT is now standard of care for anterior circulation LVO up to 24 hours from last known normal time.

Conclusions:

  • EVT represents a paradigm shift in AIS treatment, moving beyond time-based criteria.
  • Individualized treatment decisions based on salvageable brain tissue are crucial.
  • Further research is needed for posterior circulation and distal occlusions, and small vessel revascularization techniques.