Using decalcified collagen scaffolds to improve healing after transoral partial glossectomy for squamous cell...

Transoral partial glossectomy procedures for small squamous cell carcinomas of the anterior tongue often leave significant defects which are challenging to reconstruct. Post-operative scarring leads to adhesions, reduced tongue mobility and limitations of function. We present a series of cases where a decalcified collagen scaffold was successfully used in this challenging reconstructive setting.

After standard oncological diagnostic and workup, five patients underwent transoral partial glossectomy procedures. Decalcified collagen scaffolds were used to reconstruct the surgical defect using a standard protocol. Demographic and outcome data were collected retrospectively.

The median length of post-operative stay was 5 days. There was no reported post-operative bleeds or infection. Histological margins were clear. Scaffolds remained in situ at 1 week, and functional recovery was apparent at 6 weeks post-procedure.

These results suggest such scaffolds could be used as an adjunct to help reconstruct the anterior tongue after oncological resection.

The study supports a call for further exploration and research into the use of these scaffolds as a potentially beneficial avenue for reconstructing the tongue.