Modulation of seminal fluid molecules by males and females

In insects, seminal fluid molecules (SFMs) influence female post-mating phenotypes that affect reproductive success including egg development, sperm use, mating behavior, attractiveness, and lifespan. Yet, the magnitude of these effects can be quite variable, even within inbred strains. This variation is important because it could impact post-copulatory reproductive success of both males and females. One likely cause of this variation is modulation by males or females of the quantities or qualities (e.g. stability or activity state) of SFMs, or, in the case of females, of their sensitivity to SFMs. Here, I review opportunities for SFM modulation by males and females and propose that these processes could provide mechanisms by which information received before and during copulation influences post-copulatory reproductive success.