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Related Experiment Video

Updated: Jan 20, 2026

Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia
10:35

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Cerebral asymmetry during development using linear measures from MRI.

Robert C Vannucci1, Linda A Heier2, Susan J Vannucci3

  • 1Department of Anthropology, Florida Atlantic University, Boca Raton, FL, USA.

Early Human Development
|September 2, 2019
PubMed
Summary
This summary is machine-generated.

Human brain asymmetry shows consistent patterns in frontal and occipital lobes across development. These cerebral hemispheric differences in width, length, and height do not significantly change with age or sex.

Keywords:
Cerebral hemispheresDifferencesMRIMaturationSex

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Area of Science:

  • Neuroscience
  • Human Anatomy
  • Developmental Biology

Background:

  • Human brain asymmetry is a recognized phenomenon.
  • Limited research exists on its developmental trajectory during postnatal life.
  • Understanding these changes is crucial for developmental neuroscience.

Purpose of the Study:

  • To investigate cerebral hemispheric asymmetries throughout postnatal development.
  • To quantify the extent and nature of these asymmetries in infants, children, and adolescents.
  • To examine age and sex-related differences in brain asymmetry and petalias.

Main Methods:

  • Linear measurements of brain structures in 121 individuals (infants to adolescents).
  • Statistical analysis to determine cerebral hemispheric asymmetries.
  • Assessment of frontal and occipital petalias and their relationship with age and sex.

Main Results:

  • The frontal lobe is wider on the right; the occipital lobe is wider on the left.
  • No significant differences in cerebral hemispheric length or height were observed.
  • Petalias (right frontal and left occipital) are common, increase with age absolutely, but not relative to brain size, and show no major sex differences.

Conclusions:

  • Cerebral hemispheric asymmetries exhibit specific patterns from early postnatal life.
  • Brain asymmetry dimensions do not strongly correlate with age when scaled to brain size.
  • Findings offer novel insights into the developmental patterns of human brain asymmetry.