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Related Concept Videos

Inducing Apical Periodontitis in Mice10:26

Inducing Apical Periodontitis in Mice

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Here, we present a protocol to locally induce apical periodontitis in mice. We show how to drill a hole in the mouse's tooth and expose its pulp, in order to cause local inflammation. Analysis methods to investigate the nature of this inflammation, such as micro-CT and histology, are also...
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In this study, a rat model of induction of periodontitis is presented via a combination of retentive ligature and repetitive injections of lipopolysaccharide derived from Porphyromonas gingivalis, over 14 days around the first maxillary molars. The ligation and LPS injection techniques were effective in inducing peridontitis, resulting in alveolar bone loss and inflammation.
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Related Experiment Video

Updated: Jan 20, 2026

Inducing Apical Periodontitis in Mice
10:26

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Effect of Periodontal Parameters on Root Coverage.

Thaís Ribeiral Vieira1, Dhelfeson Willya Douglas de Oliveira2, Frederico Santos Lages2

  • 1Department of Periodontology, Dentistry Faculty, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. thaisrv@terra.com.br.

Journal of the International Academy of Periodontology
|September 2, 2019
PubMed
Summary

Gingival recession height, keratinized mucosa, and free gingival margin thickness significantly influence root coverage outcomes when using the coronally positioned flap (CPF) technique for treating gum recession.

Keywords:
coronally positioned flapgingival recessiongingival thicknesskeratinized mucosaroot coverage

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Area of Science:

  • Periodontology
  • Periodontal Surgery
  • Regenerative Dentistry

Background:

  • Gingival recession is a common condition affecting oral health.
  • The coronally positioned flap (CPF) technique is a surgical option for root coverage.
  • Understanding factors influencing CPF success is crucial for predictable outcomes.

Purpose of the Study:

  • To assess the impact of various periodontal clinical parameters on the success of gingival recession treatment using the CPF technique.
  • To identify key predictors of root coverage efficacy with CPF surgery.

Main Methods:

  • A clinical study involving 14 patients with 39 cases of Miller's Class I or II gingival recession.
  • Evaluation of parameters including probing depth, recession height/width, attachment level, keratinized mucosa, and tissue thickness before and after CPF surgery.
  • Statistical analysis using t-tests, Mann-Whitney, Pearson's correlation, and Cohen's d to determine parameter influence.

Main Results:

  • Significant reductions in gingival recession height and width were observed post-surgery.
  • Keratinized mucosa and gingival thickness showed significant changes, with increased free gingival margin thickness.
  • Initial gingival recession height, keratinized mucosa, and free gingival margin thickness were strongly correlated with root coverage outcomes.

Conclusions:

  • Initial gingival recession height, keratinized mucosa, and free gingival margin thickness are critical factors for successful root coverage with the CPF technique.
  • These parameters should be carefully considered during treatment planning for gingival recession.
  • The CPF technique demonstrates effectiveness, with specific initial conditions influencing the degree of root coverage achieved.