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Updated: Jan 20, 2026

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
[Progress in cohort studies related to injury]
1Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.
Global injury cohort studies show a peak around 2000. While many studies exist worldwide, China has few, highlighting a need for more large-scale, multi-center injury research.
Area of Science:
- Public Health
- Epidemiology
- Injury Prevention
Background:
- Injury remains a significant global health concern.
- Cohort studies are crucial for understanding injury causes and outcomes.
- A comprehensive summary of existing injury cohort studies is needed.
Purpose of the Study:
- To systematically review and summarize the progress of global injury cohort studies.
- To identify trends in publication, study characteristics, and common injury types.
- To assess the landscape of injury cohort research, particularly in China.
Main Methods:
- A systematic literature search was conducted in PubMed, WanFang, and CNKI databases for publications before December 2017.
- Data extracted included study design, injury category, population, sample size, country, follow-up duration, exposures, outcomes, and data collection methods.
- A total of 295 injury cohort studies were analyzed.
Main Results:
- The number of injury cohort studies peaked around the year 2000 and has since declined.
- The United States, Sweden, and the United Kingdom are leading countries in injury cohort publications.
- Suicide/self-harm, falls, and road traffic injuries were the most common causes studied; China has a limited number of published cohorts.
Conclusions:
- Numerous injury cohort studies have been established globally, but few originate from mainland China.
- Existing global studies provide valuable references for designing future large-scale, multi-center injury cohorts in China.
- Further development of high-quality injury cohort research in China is recommended.
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