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Updated: Jan 20, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Black aortic valve: Minocycline pigmentation complicating treatment of pyoderma gangrenosum
Tomoki Nagata1, Takao Hasegawa2, Hiroyuki Johno1
1Department of Cardiovascular Surgery, Takaishi Fujii Cardiovascular Hospital, Osaka, Japan.
Abstract:
We describe the case of a 75-year-old male with pyoderma gangrenosum (PG) who had severe aortic insufficiency and moderate mitral regurgitation. He had been taking minocycline for 15 years to treat PG. He underwent aortic valve replacement and mitral valve repair. Aortotomy revealed a black discoloration of the aortic valve and sinus of Valsalve.
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