Related Experiment Video
Updated: Jan 20, 2026
08:42
Establishment of Gastric Cancer Patient-derived Xenograft Models and Primary Cell Lines
Published on: July 19, 2019
10.7K
Atherosclerosis in cancer patients
Bratislavske Lekarske Listy
|September 3, 2019
Summary
Cancer survivors face increased cardiovascular risk due to treatments. This review details atherosclerosis risk factors and mechanisms linked to cancer therapies, highlighting a growing concern in oncology.
Area of Science:
- Oncology
- Cardiology
- Cardio-oncology
Background:
- Cancer mortality rates have declined, leading to more long-term survivors.
- Increased survival is offset by a rising incidence of cardiovascular disease in cancer patients.
- Atherosclerotic damage has been historically underestimated in cancer care.
Purpose of the Study:
- To review cardiovascular risk factors associated with cancer therapies.
- To elucidate pathophysiological mechanisms of atherosclerosis induced by cancer treatments.
- To present recent clinical data on atherosclerosis in cancer patients.
Main Methods:
- Literature review of cardiovascular risk factors.
- Analysis of pathophysiological mechanisms of atherosclerosis.
- Synthesis of recent clinical data on atherosclerosis in oncology.
Main Results:
- Chemotherapeutics, targeted therapies, hormonal agents, and radiotherapy can induce or exacerbate atherosclerosis.
- Cancer patients exhibit significant cardiovascular risk factors and arterial disease during and after treatment.
- Atherosclerosis in cancer patients presents complex challenges.
Conclusions:
- Cardiovascular risk, particularly atherosclerosis, is a critical concern for cancer patients and survivors.
- Understanding treatment-induced atherosclerosis is vital for comprehensive cancer care.
- Further research and clinical attention are needed to manage cardio-oncology risks.
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