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Updated: Jan 20, 2026

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Severe transient neonatal long QT syndrome due to maternal paroxetine usage: a case report

Eeke C M Leerssen1, Ramon O Tak1, Johannes M P J Breur1

  • 1Department of Paediatric Cardiology, University Medical Centre/Wilhelmina Children's Hospital, Utrecht, the Netherlands.

Cardiology in the Young
|September 3, 2019
PubMed

A female neonate with in utero selective serotonin reuptake inhibitor exposure presented with bradycardia shortly after birth. Electrocardiography showed severe QT prolongation and second-degree atrioventricular block. Over time QT-times spontaneously normalised and genetic testing did not show mutations associated with long QT syndrome making maternal selective serotonin reuptake inhibitor usage the most likely explanation for the observed severe transient neonatal QT prolongation.

Keywords:
Long QT syndromein utero exposureneonateparoxetineselective serotonin reuptake inhibitor

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