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Updated: Jan 20, 2026
Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients
Published on: November 19, 2019
[Serum cellular inflammatory markers in the diagnosis of prostate cancer.]
Alessandri R Espinoza1, Jasson Lavi2, Natalia Otaño1
1Médico Especialista adscrito al Servicio de Urología. Hospital Universitario de Caracas. Universidad Central de Venezuela.
Abstract:
Prostate cancer (PCa) is one of the most frequent neoplasms in the masculine sex, which has multiple etiological factors, inflammation is one of them.
Objective:
To determine the role of different inflammatory markers in the diagnosis of PCa in first prostatic biopsies.
Methods:
This is a prospective study evaluating neutrophil/ lymphocyte (NLR), neutrophil/monocyte (NMR) and platelet/lymphocyte (PLR) ratios of 78 patients with suspected PCa due to PSA alteration and/or abnormal digital rectal examination, and its correlation with twelve-cylinder biopsy result.
Results:
The NLR, NMR and PLR were all higher in the group diagnosed with PCa compared to the group with benign prostatic hyperplasia (p > 0.05).
Conclusions:
Inflammatory markers can be predictive factors in the diagnosis of PCa, although more studies are needed for their routine use.
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