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Updated: Jan 20, 2026

An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
Practical approach to the management of catheter-related bloodstream infection
M L Cantón-Bulnes, J Garnacho-Montero1
1José Garnacho-Montero, Unidad de Cuidados Intensivos, Hospital Universitario Virgen Macarena, Sevilla, Spain. jgarnachom@gmail.com.
Insights
Catheter-related bloodstream infections (CRBSI) pose significant risks. This review highlights updated 2018 guidelines for diagnosing and managing adult CRBSI, focusing on empirical and targeted therapies.
Area of Science:
- Infectious Diseases
- Critical Care Medicine
- Clinical Microbiology
Background:
- Catheter-related bloodstream infections (CRBSI) are a frequent cause of hospital-acquired infections.
- CRBSI leads to increased patient morbidity, mortality, extended hospital stays, and healthcare expenses.
- Updated clinical practice guidelines for CRBSI management in adults were published in 2018.
Purpose of the Study:
- To review updated recommendations for diagnosing and managing CRBSI in adult patients.
- To focus on key aspects of CRBSI diagnosis and treatment.
- To exclude CRBSI prevention strategies from the review.
Main Methods:
- Review of the 2018 clinical practice guidelines from SEIMC and SEMICYUC.
- Focus on diagnostic criteria for CRBSI.
- Analysis of empirical and targeted therapeutic strategies for CRBSI.
Main Results:
- The review synthesizes updated diagnostic approaches for CRBSI.
- Key recommendations for empirical and targeted therapy are presented.
- The guidelines provide a framework for effective CRBSI management.
Conclusions:
- Updated guidelines offer crucial information for the diagnosis and management of adult CRBSI.
- Adherence to these recommendations can improve patient outcomes.
- This review emphasizes the importance of timely and appropriate CRBSI treatment.
Abstract:
Catheter-related bloodstream infections (CRBSI) is a common cause of nosocomial infection associated resulting in substantial morbidity, mortality, increased length of hospital stays and health-care costs. New clinical practice guidelines for the management of adults with CRBSI have been published in 2018 by the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC). This review focuses on updated recommendations for the diagnosis and management of CRBSI in adults. Prevention of CRBSI is excluded. Our aim is to show some of the key aspects concerning the following topics: diagnosis, empirical and targeted therapy.
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