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Related Experiment Videos

Gonorrhea in the newborn.

E R Alexander1

  • 1Division of Sexually Transmitted Diseases, Centers for Disease Control, Atlanta, Georgia 30333.

Annals of the New York Academy of Sciences
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

Gonorrhea in pregnant women is usually low, but high rates in some US adolescent clinics are concerning. Risks to newborns include ophthalmia neonatorum and rare disseminated infections.

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Area of Science:

  • Reproductive Health
  • Infectious Diseases
  • Maternal-Fetal Medicine

Background:

  • Gonorrhea prevalence in pregnant women in the US is typically low (<1%).
  • Elevated rates (up to 10%) observed in specific populations, such as urban adolescent prenatal clinics, mirror those in developing countries.
  • Maternal gonorrhea is a known risk factor for ophthalmia neonatorum in newborns (30%-40% transmission).

Purpose of the Study:

  • To summarize the current understanding of gonorrhea prevalence in pregnant women in the United States.
  • To highlight specific populations with elevated risk.
  • To review the known and potential risks of gonorrhea transmission to newborns.

Main Methods:

  • Review of existing literature on gonorrhea prevalence in pregnant populations.

Related Experiment Videos

  • Analysis of transmission risks to newborns, including ophthalmia neonatorum and disseminated gonococcal infection.
  • Consideration of the impact of antimicrobial resistance, specifically penicillinase-producing Neisseria gonorrheae (PPNG).

    • Main Results:

    • While overall US prevalence is low, certain adolescent and urban populations show significantly higher rates.
    • Neonatal transmission risks for ophthalmia neonatorum are substantial (30%-40%).
    • Risks of neonatal sepsis or arthritis from disseminated gonococcal infection are considered rare.
    • Maternal gonorrhea may be linked to premature delivery, a finding suggested in US studies and more established in developing countries.
    • Penicillinase-producing Neisseria gonorrheae (PPNG) necessitates alternative treatment but does not appear to alter transmission dynamics.

    Conclusions:

    • Gonorrhea remains a concern in specific pregnant populations in the US, requiring targeted screening and management.
    • Effective treatment and prevention strategies are crucial to mitigate neonatal risks, including ophthalmia neonatorum and potential premature delivery.
    • Antimicrobial resistance necessitates adaptable therapeutic approaches without altering the fundamental transmission risks to the neonate.