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Updated: Jan 20, 2026
Role of Hematopoietic Growth Factors
The role of concentrated growth factor on implant stability: A preliminary study
B Özveri Koyuncu1, K İçpınar Çelik2, M Özden Yüce1
1Department of Oral Surgery, School of Dentistry, Ege University, 35040, Bornova, İzmir, Turkey.
Purpose:
The purpose of this preliminary study was to evaluate the effect of concentrated growth factor (CGF) on dental implant stability in type 2 bone using the resonance frequency analysis (RFA) device Smartpeg®.
Methods:
The researchers carried out a prospective cohort study on a sample group composed of 12 patients (mean age=67) who required dental implants. Implant socket preparation (with and without CGF) was the primary predictor variable. In each patient, two dental implants were inserted in the anterior mandible. For the test group, one dental implant socket was covered with CGF membrane, while the other socket was prepared conventionally for the control group. Implant stability, as measured by RFA, was the outcome variable. Measurements were taken using the Ostell device at the time of implant placement and at the 1st, 2nd and 4th weeks.
Results:
Mean implant stability quotients (ISQs) were 67.00±4.573 for the study group and 64.75±5.065 for the control group. The difference between the two groups was not statistically significant.
Conclusion:
It was found that CGF did not provide beneficial effect on dental implant stability in the early healing period in type 2 bone.
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