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Related Experiment Videos

4D cardiac electromechanical activation imaging.

Julien Grondin1, Dafang Wang2, Christopher S Grubb3

  • 1Department of Radiology, Columbia University, 630 W 168th, Street, New York, NY, 10032, USA.

Computers in Biology and Medicine
|September 3, 2019
PubMed
Summary

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Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

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Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
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This summary is machine-generated.

A new noninvasive 4D ultrasound technique maps the heart's electrical activity in real-time. This breakthrough allows for precise localization of cardiac abnormalities like arrhythmia and infarction, improving diagnosis and patient care.

Area of Science:

  • Biomedical Engineering
  • Cardiology
  • Medical Imaging

Background:

  • Cardiac abnormalities are a leading cause of death globally.
  • Current diagnostic methods lack noninvasive, 3D visualization of the entire heart's electrical function.
  • Early diagnosis and precise localization of cardiac issues remain critical clinical challenges.

Purpose of the Study:

  • To introduce a novel noninvasive method for 4D electromechanical mapping of cardiac activity.
  • To enable real-time characterization of heart diseases, including arrhythmia and infarction.
  • To provide a point-of-care tool for localizing cardiac abnormalities.

Main Methods:

  • Utilized high volume-rate (500 volumes/sec) ultrasound with a 32x32 matrix array.
  • Developed a technique to capture the 3D cardiac activation wave in vivo within a single heartbeat.
Keywords:
3D activation mapping3D ultrasoundCardiac activation mappingCardiac arrhythmiaElectromechanical wave imagingHigh frame rate ultrasound

Related Experiment Videos

  • Generated in silico and in vivo electromechanical activation maps.

    • Main Results:

    • Successfully demonstrated noninvasive 4D electromechanical activation mapping in normal and infarcted cardiac models.
    • Validated the technique in canine hearts during pacing and ventricular tachycardia.
    • Obtained 4D electromechanical activation maps in a healthy volunteer and a heart failure patient.

    Conclusions:

    • The novel technique offers direct, simultaneous, and noninvasive 3D visualization of cardiac electromechanical activation.
    • This method provides complementary information on myocardial viability and abnormalities.
    • It holds potential for improved diagnosis and management of heart disease.