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Updated: Jan 20, 2026

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[Influenza].

C Malainou1, S Herold2

  • 1Medizinische Klinik II, Universitätsklinikum Gießen und Marburg (UKGM), Klinikstr. 33, 35392, Gießen, Deutschland.

Der Internist
|September 4, 2019
PubMed
Summary
This summary is machine-generated.

Influenza virus infections cause significant mortality and morbidity in Europe, transmitted via aerosols. Early PCR diagnosis and neuraminidase inhibitor treatment are key, alongside improved seasonal influenza vaccination rates.

Keywords:
Acute respiratory distress syndromeInfluenza vaccines, seasonalNeuraminidase inhibitorsPneumonia, viral, influenzaPolymerase chain reaction

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Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • Influenza virus (IV) infections contribute significantly to mortality and morbidity across Europe.
  • The incidence of IV infections is often underrecognized despite its substantial public health impact.

Purpose of the Study:

  • To provide a comprehensive overview of influenza virus pathogenesis.
  • To outline current strategies for optimizing diagnostics and treatment based on existing guidelines and clinical trials.

Main Methods:

  • Conducted a literature search and analysis of national and international guidelines.
  • Focused on epidemiology, diagnostics, treatment, and prevention of IV infections.

Main Results:

  • Influenza virus is the leading infectious cause of mortality and morbidity in Europe, transmitted mainly by aerosol inhalation.
  • Symptoms range from mild to severe respiratory failure; PCR testing is recommended for clinical diagnosis verification.
  • Neuraminidase inhibitors are the primary treatment, and seasonal vaccination is an effective preventive measure.

Conclusions:

  • Improving influenza vaccination rates in Germany is crucial, as they have declined since 2009/2010.
  • Effective management relies on prompt diagnosis, appropriate antiviral treatment, and robust vaccination programs.