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Updated: Jan 20, 2026

Mammalian Cell Division in 3D Matrices via Quantitative Confocal Reflection Microscopy
Published on: November 29, 2017
Quantitative evaluation of atrophic acne scars using 3D image analysis with reflected LED light
Hideaki Tanizaki1, Miki Tanioka2, Yuki Yamashita3
1Department of Dermatology, Osaka Medical College, Osaka, Japan.
Three-dimensional image analysis offers a reliable method for objectively evaluating acne scars. This technique accurately quantifies scar severity and count, aiding in treatment assessment.
Area of Science:
- Dermatology
- Medical Imaging
- Aesthetic Medicine
Background:
- Objective evaluation methods for acne scars are currently lacking.
- This study investigates the potential of 3D image analysis for assessing acne scarring.
Purpose of the Study:
- To examine the capability of 3D image analysis in evaluating acne scarring.
- To determine the correlation between objective 3D measurements and dermatologists' assessments of acne scars.
Main Methods:
- Two dermatologists assessed atrophic acne scar severity and count in a defined cheek area (3.5cm x 3.5cm) for 22 subjects.
- An Antera 3D camera captured images, measuring affected area, volume, and maximum depth using different filters.
- Spearman's correlation coefficients analyzed relationships between 3D parameters and dermatological evaluations.
Main Results:
- The 'large' filter demonstrated the highest correlation with dermatologists' evaluations.
- Strong correlations were found between scar severity and affected area (0.736), volume (0.728), and max depth (0.722).
- Scar counts correlated highly with affected area (0.783) and volume (0.770), indicating good repeatability.
Conclusions:
- 3D image analysis shows significant capability for objective acne scar evaluation.
- This technology can quantitatively assess changes in scar morphology before and after treatment.
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