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Related Experiment Video

Updated: Jan 20, 2026

Stimulating Nerve Stem Cell Differentiation Using Cold Atmospheric Plasma Treatment
02:20

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Treatment of the Common Cold.

Katharine C DeGeorge1, Daniel J Ring1, Sarah N Dalrymple1

  • 1University of Virginia Department of Family Medicine, Charlottesville, VA, USA.

American Family Physician
|September 4, 2019
PubMed
Summary

Effective treatments for common cold symptoms in adults include analgesics and zinc. For children, safe options include honey and nasal saline, but over-the-counter cold medicines are not recommended for those under four.

Area of Science:

  • General Medicine
  • Pediatrics
  • Pharmacology

Background:

  • Acute upper respiratory tract infections (URTIs), commonly known as the common cold, are highly prevalent in both adults and children.
  • Despite their frequency, a limited number of safe and effective treatment options are available for managing cold symptoms.
  • Typical symptoms include nasal congestion, rhinorrhea, sore throat, cough, malaise, and low-grade fever.

Purpose of the Study:

  • To review and summarize the established safe and effective treatments for common cold symptoms in adults and children.
  • To provide evidence-based recommendations for managing URTIs and preventing their transmission.

Main Methods:

  • Review of existing literature and clinical guidelines on the treatment of acute upper respiratory tract infections.

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  • Identification of interventions with proven effectiveness for specific cold symptoms in different age groups.

    • Main Results:

    • For adults, effective treatments include over-the-counter analgesics, zinc, nasal decongestants (with or without antihistamines), and ipratropium for cough.
    • For children, established safe and effective treatments include acetylcysteine, honey (for those aged one year and older), nasal saline irrigation, intranasal ipratropium, and topical ointments containing camphor, menthol, and eucalyptus oils.
    • Over-the-counter cold medications are not recommended for children under four years of age.

    Conclusions:

    • Informing patients about the self-limited nature of the common cold is crucial for managing expectations and reducing unnecessary antibiotic use.
    • Good hand hygiene is the most effective preventive measure against the transmission of cold viruses.
    • Treatment strategies should be age-specific, prioritizing safety and efficacy, especially in pediatric populations.