Who Benefits from an Expanding Pool of Matriculants?

Self-esteem—an individual's overall evaluation of their worth—plays a complex role in psychological functioning and well-being. It is often associated with many positive traits, such as confidence, optimism, and perseverance. Individuals with high self-esteem typically experience better sleep, manage peer pressure more effectively, and report greater life satisfaction. Conversely, low self-esteem has been consistently linked with increased risks of depression, anxiety, and poor...

Source: Laboratories of Nicholaus Noles, Judith Danovitch, and Asheley Landrum—University of Louisville
Children have many tools they use over the course of development to learn from adults. Perhaps the earliest tool is imitation, simply copying what they see an adult do or say. However, children actually learn much more effectively than one might expect if they were only imitating. This is because, when it comes to learning and teaching, children and adults have a special relationship....

CRISPR-Cas9 technology provides an efficient method to precisely edit the mammalian genome in any cell type and represents a novel means to perform genome-wide genetic screens. A detailed protocol discussing the steps required for the successful performance of pooled genome-wide CRISPR-Cas9 screens is provided...

External marginal costs are additional costs imposed on third parties when one more unit of a good or service is produced or consumed. These costs are not borne by the producer or consumer but by others outside the market exchange.
External marginal benefits are additional benefits received by third parties when one more unit of a good or service is produced or consumed. These benefits are not received by the producer or consumer but by others outside the market exchange.
Social costs include...

Here we use a human LentiPlex pooled library and traditional sequencing methods to identify gene targets promoting cell survival. We demonstrate how to set up and deconvolute a LentiPlex screen and validate the...

Private costs are the expenses that businesses or individuals incur in a market exchange when producing or purchasing a good. These costs include everything spent directly by the supplier to make and deliver the product to market or everything spent by the consumer to purchase the product.
For instance, in a coffee shop, private costs to the producer include the price of coffee beans, milk, sugar, employee wages, utility bills, and all the other expenses that go into selling coffee. In a...