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Updated: Jan 20, 2026
Reactive Oxygen Species and Oxidative Stress
Published on: April 30, 2023
Alternative Oxidase Is Involved in the Pathogenicity, Development, and Oxygen Stress Response of Botrytis cinerea
Zesong Lin1, Jianyan Wu1, Pierce A Jamieson2
1Department of Crop Protection, Zhejiang Agriculture and Forest University, Hangzhou 311300, China.
Abstract:
Alternative oxidase (AOX) is a ubiquinol terminal oxidase that is involved in fungal mitochondrial oxidative phosphorylation. In this study, we analyzed the roles of AOX in Botrytis cinerea by generating BcAOX deletion mutants. The mutants exhibited defects in mycelial growth, sporulation, spore germination, and virulence. Furthermore, the sensitivity of the mutants to quinone outside inhibitor fungicides and oxidative stress were increased. All phenotypic variations could be restored in the complemented strain. In summary, these results showed that BcAOX is involved in the regulation for vegetative development, adaptation to environmental stress, and virulence of B. cinerea.
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