Related Experiment Video
Updated: Jan 20, 2026

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
Natural orifice specimen extraction (NOSE) surgery with rectal eversion and total extra-abdominal resection
S K Efetov1, I A Tulina2, V D Kim2
1Clinic of Colorectal and Minimally Invasive Surgery, I.M. Sechenov First Moscow State Medical University (Sechenov University), 2-4 Bolshaya Pirogovskaya st., Moscow, 119991, Russia. efetov@mail.ru.
Background:
Natural orifice specimen extraction (NOSE)surgery is gaining popularity among colorectal surgeons. The technical aspects of this new procedure are still debated and many variations have been presented in the last decade.
Methods:
We propose a new variation of transanal NOSE after robotic and laparoscopic LAR consisting of rectal eversion by using a special rod after laparoscopic TME. Eversion makes it possible to perform resection and placement of the anvil extracorporeally. We included a video demonstration of the technique. Clinical Patient Grading Assessment Scale was calculated 1 month after stoma closure and the Low Anterior Resection Syndrome (LARS )score was calculated preoperatively and 1 month after stoma closure.
Results:
Seven female patients with rectal cancer, all with normal BMI, underwent laparoscopic (n = 5) or robotic (n = 2) TME with rectal eversion. No intraoperative and postoperative complications were reported. One month after stoma closure, the median Clinical Patient Grading Assessment Scale was 5 (range 3-7), which means "a good deal better". The median LARS score was 14 (IQR 14-19,5) preoperatively and 19 (IQR 19-21,5) 1 month after stoma closure.
Conclusions:
This variation of NOSE surgery was safe and effective in our patient population.
Related Concept Videos
08:26Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
07:22Surgical Robot-Assisted Transanal Specimen Extraction Radical Sigmoidectomy Without an Auxiliary Abdominal Incision
06:40An In Vivo Mouse Model of Total Intravenous Anesthesia During Cancer Resection Surgery
06:13Endoscopic Septoplasty with Limited Two-line Resection: Minimally Invasive Surgery for Septal Deviation
02:22Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
04:40Augmented Reality-Based Visualization of a Resected Tumor Specimen

