Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Random Sampling Method01:09

Random Sampling Method

14.2K
Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. Data are the result of sampling from a population. The sampling method ensures that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest. Among the various sampling methods used by...
14.2K
Recording Brain Electrical Activity in Behaving Mice Using Multi-Shank Linear Silicon Probes03:22

Recording Brain Electrical Activity in Behaving Mice Using Multi-Shank Linear Silicon Probes

688
This video outlines a protocol for implanting a multi-shank linear silicon probe into the mouse brain to measure local field potentials. The procedure involves securing the probe to a stereotaxic unit, positioning it accurately over the target brain region, inserting it into the brain, and securing it with dental cement. After implantation, the assembly is protected with a casing. Following recovery, the setup allows for recording local field potentials, providing insights into neuronal...
688
Biomembrane Force Probe to Quantitate Receptor-Ligand Interactions05:57

Biomembrane Force Probe to Quantitate Receptor-Ligand Interactions

547
In this video, biomembrane force probes (BFPs) are used to measure the forces between receptors and ligands. This technique can detect interactions by monitoring the pressure needed to break the bonds between the pMHC conjugated on the probe beads and the TCRs on the target...
547
Solid Phase Microextraction Sampling: A Probe-based Technique for Sample Extraction from Graft Tissues03:42

Solid Phase Microextraction Sampling: A Probe-based Technique for Sample Extraction from Graft Tissues

3.4K
In this video, we demonstrate SPME-probe-based extraction of metabolites from a pre-harvested donor kidney. The extracted metabolites can be used to perform metabolomic and lipidomic analysis in order to assess the organ quality for...
3.4K
Curvilinear Motion: Rectangular Components01:23

Curvilinear Motion: Rectangular Components

1.1K
Curvilinear motion characterizes the movement of a particle or object along a curved path, notably evident when envisioning a car navigating a winding road. If the car starts at point A, its position vector is established within a fixed frame of reference, where the ratio of the position vector to its magnitude signifies the unit vector pointing in the position vector's direction.
As the car advances, its position evolves over time. Quantifying the car's velocity involves computing the...
1.1K
Curvilinear Motion: Polar Coordinates01:27

Curvilinear Motion: Polar Coordinates

869
In polar coordinates, the motion of a particle follows a curvilinear path. The radial coordinate symbolized as 'r,' extends outward from a fixed origin to the particle, while the angular coordinate, 'θ,' measured in radians, represents the counterclockwise angle between a fixed reference line and the radial line connecting the origin to the particle.
The particle's location is described using a unit vector along the radial direction. Deriving the particle's position...
869

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanomyography is more sensitive than EMG in detecting age-related sarcopenia.

Journal of biomechanics·2009
Same author

Phylogenomic analyses predict sistergroup relationship of nucleariids and fungi and paraphyly of zygomycetes with significant support.

BMC evolutionary biology·2009
Same author

Evolution of an X-linked primate-specific micro RNA cluster.

Molecular biology and evolution·2009
Same author

mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells.

Science signaling·2009
Same author

Proteomic analysis of mitochondria reveals a metabolic switch from fatty acid oxidation to glycolysis in the failing heart.

Science in China. Series C, Life sciences·2009
Same author

Characterization and catalytic performance of porous carbon prepared using in situ-formed aluminophosphate framework as template.

Journal of colloid and interface science·2009

Related Experiment Video

Updated: Jan 20, 2026

Random Sampling Method
01:09

Random Sampling Method

14.2K

Probing curvilinear-by-linear interactions when the predictors are randomly sampled.

Yu Liu1

  • 1Department of Psychological, Health, and Learning Sciences, University of Houston, Houston, TX, USA. yliu207@central.uh.edu.

Behavior Research Methods
|September 5, 2019
PubMed
Summary

Researchers often analyze curvilinear effects in social sciences. Treating predictor variables as fixed, rather than random, can lead to inaccurate statistical results when testing interactions.

Keywords:
BootstrapCurvilinear interactionFixed regressionFully BayesianRandom regression

More Related Videos

Recording Brain Electrical Activity in Behaving Mice Using Multi-Shank Linear Silicon Probes
03:22

Recording Brain Electrical Activity in Behaving Mice Using Multi-Shank Linear Silicon Probes

688
Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy
13:15

Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy

Published on: July 18, 2014

11.4K

Related Experiment Videos

Last Updated: Jan 20, 2026

Random Sampling Method
01:09

Random Sampling Method

14.2K
Recording Brain Electrical Activity in Behaving Mice Using Multi-Shank Linear Silicon Probes
03:22

Recording Brain Electrical Activity in Behaving Mice Using Multi-Shank Linear Silicon Probes

688
Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy
13:15

Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy

Published on: July 18, 2014

11.4K

Area of Science:

  • Social and behavioral sciences
  • Quantitative psychology
  • Statistical modeling

Background:

  • Curvilinear effects and interactions are common in social and behavioral research.
  • Traditional methods for testing these effects often assume predictors are fixed.
  • Randomly sampled predictors are more typical in many research contexts.

Purpose of the Study:

  • To investigate the impact of sampling assumptions on statistical inference for curvilinear-by-linear interactions.
  • To compare fixed versus random regression models in the context of predictor sampling.
  • To identify potential sources of error in common analytical approaches.

Main Methods:

  • Analytical derivations comparing fixed and random regression models.
  • Monte Carlo simulations to evaluate statistical performance under different sampling schemes.
  • Examination of simple slope tests and Johnson-Neyman technique under varying conditions.

Main Results:

  • Fixed and random regression models yield identical parameter estimates.
  • Standard errors for simple slopes differ significantly between fixed and random models.
  • Incorrectly treating randomly sampled predictors as fixed inflates Type I error rates and compromises confidence interval coverage.

Conclusions:

  • The assumption of predictor sampling (fixed vs. random) critically impacts statistical inference for curvilinear-by-linear interactions.
  • Researchers should carefully consider the nature of their predictor variables.
  • Current practices may lead to inflated Type I errors, necessitating revised analytical strategies.