Related Experiment Video

Updated: Jan 20, 2026

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling
09:33

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling

Published on: March 20, 2018

14.3K

The first hydride-Meisenheimer adduct of electron-deficient 3-nitronaphthalimide: application to colorimetric

Myung Gil Choi1, Na Yeong Kim, Yu Jeong Lee

  • 1Department of Chemistry, Chung-Ang University, Seoul 06974, Republic of Korea. sangdoo@cau.ac.kr skchang@cau.ac.kr.

Chemical Communications (Cambridge, England)
|September 5, 2019
PubMed

More Related Videos

Lewis Acid-Base Interaction in Ph3P-BH309:00

Lewis Acid-Base Interaction in Ph3P-BH3

Published on: April 30, 2023

41.0K
Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate06:46

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Published on: June 21, 2017

7.9K

Related Concept Videos

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling09:33

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling

Evaluating the potency of environmental chemicals and drugs, to be enzymatically bioactivated to intermediates generating covalent DNA adducts, is an important field in the development of cancer and its treatment. Methods are described for compound activation to form DNA adducts, as well as techniques for their detection and...
14.3K
Lewis Acid-Base Interaction in Ph3P-BH309:00

Lewis Acid-Base Interaction in Ph3P-BH3

Source: Tamara M. Powers, Department of Chemistry, Texas A&M University 
One of the goals of chemistry is to use models that account for trends and provide insights into the properties of reactants that contribute to reactivity. Substances have been classified as acids and bases since the time of the ancient Greeks, but the definition of acids and bases has been modified and expanded over the years.1
The ancient Greeks would characterize substances by taste, and defined acids as those...
41.0K
Removal of Branched and Cyclic Compounds by Urea Adduction for Uk'37 Paleothermometry07:52

Removal of Branched and Cyclic Compounds by Urea Adduction for Uk'37 Paleothermometry

Source: Laboratory of Jeff Salacup - University of Massachusetts Amherst
As mentioned in previous videos, the product of an organic solvent extraction, a total lipid extract (TLE), is often a complex mixture of hundreds, if not thousands, of different compounds. The researcher is often only interested in a handful of compounds. In the case of our two organic paleothermometers (Uk'37 and MBT/CBT), the interest is in only 6 compounds (2 alkenones and 4 isoprenoidal glycerol dialkyl glycerol...
6.8K
Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate06:46

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

The ruthenium-catalyzed olefination of electron-deficient alkenes with allyl acetate is described here. By using aminocarbonyl as a directing group, this external oxidant-free protocol has high efficiency and good stereo- and regioselectivity, opening a novel synthetic route to (Z,E)-butadiene...
7.9K
Application of Monolayer Graphene to Cryo-Electron Microscopy Grids for High-resolution Structure Determination07:57

Application of Monolayer Graphene to Cryo-Electron Microscopy Grids for High-resolution Structure Determination

The application of support layers to cryogenic electron microscopy (cryoEM) grids can increase particle density, limit interactions with the air-water interface, reduce beam-induced motion, and improve the distribution of particle orientations. This paper describes a robust protocol for coating cryoEM grids with a monolayer of graphene for improved cryo-sample...
26.3K
Design and Development of Aptamer–Gold Nanoparticle Based Colorimetric Assays for In-the-field Applications08:23

Design and Development of Aptamer–Gold Nanoparticle Based Colorimetric Assays for In-the-field Applications

The design and development of an aptamer–gold nanoparticle colorimetric assay for the detection of small molecules for in-the-field applications was examined. Additionally, a smart-device colorimetric application (app) was validated and long-term storage of the assay was established for use in the...
12.7K