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Related Concept Videos

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase07:27

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The fate of the replisome following a collision with a head-on RNA polymerase (RNAP) is unknown. We find that the replisome stalls upon collision with a head-on RNAP, but resumes elongation after displacing the RNAP from DNA. Mfd promotes replication restart by facilitating displacement of the RNAP after the...
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A cyclic pressure bioreactor capable of subjecting heart valve tissue to physiological and pathological pressure conditions has been designed. A LabVIEW program allows users to control pressure magnitude, amplitude and frequency. This device can be used to study the mechanobiology of heart valve tissue or isolated...
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Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability10:31

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To overcome the limitations of classical site-directed mutagenesis, proline analogs with specific modifications were incorporated into several fluorescent proteins. We show how the replacement of hydrogen by fluorine or of the single by double bonds in proline residues ("molecular surgery") affects fundamental protein properties, including their folding and interaction with...
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Vascular responses of arterial pulmonary circulation can be explored using intrapulmonary artery (IPA) and vascular smooth muscle cells (VSMCs). The present study describes the isolation of IPA in detail and the protocols used for investigating vasorelaxation in response to physiological...
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Related Experiment Video

Updated: Jan 20, 2026

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
07:27

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Reply to Atamanalp

C-W Hsu1,2

  • 1Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan.

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
|September 5, 2019
PubMed
Summary

No abstract available in PubMed .

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