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Updated: Jan 20, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
Published on: May 3, 2018
Chronic Standing Desk Use and Arterial Stiffness
Using standing desks for over half the workday did not impact arterial stiffness (pulse wave velocity). However, age and aerobic fitness significantly influence arterial stiffness in both seated and standing desk users.
Area of Science:
- Cardiovascular Health
- Occupational Health
- Biomedical Engineering
Background:
- Prolonged sedentary behavior (≥10 hours/day) elevates cardiovascular disease risk by over 60%.
- Standing desks offer a potential intervention to reduce sedentary time and enhance cardiovascular well-being.
- While acute standing reduces pulse wave velocity (PWV), the long-term impact of chronic standing desk use on arterial stiffness is not well understood.
Purpose of the Study:
- To investigate the chronic effects of standing desk usage on arterial stiffness.
- To compare arterial stiffness in individuals using standing desks versus traditional seated desks.
Main Methods:
- A study involving 48 adults, divided into seated (n=24) and standing (n=24) desk user groups.
- Arterial stiffness was quantified using pulse wave velocity (PWV) measurements in the aorta, arm, and leg.
- Participants' age and aerobic fitness levels were assessed as potential confounding factors.
Main Results:
- No significant differences in carotid-femoral PWV (cfPWV) were observed between the standing desk group (6.9 m/s) and the seated desk group (6.6 m/s).
- Arm and leg PWV also showed no significant differences between the two groups.
- Secondary analysis indicated that age and aerobic fitness significantly modulated cfPWV in both seated and standing desk users.
Conclusions:
- Chronic standing desk use, even for more than 50% of the workday, did not alter arterial stiffness (PWV).
- Consistent with existing literature, age and aerobic fitness remain critical determinants of arterial stiffness.
- Future research may explore other physiological markers or longer-term interventions.
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