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Related Concept Videos

The Evidence for Evolution02:55

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Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
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Related Experiment Video

Updated: Jan 20, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
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Deprescribing: Practical Ways to Support Person-Centred, Evidence-Based Deprescribing.

Katherine Le Bosquet1, Nina Barnett2, John Minshull2

  • 1Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK. Katherine.lebosquet@nhs.net.

Pharmacy (Basel, Switzerland)
|September 6, 2019
PubMed
Summary

Deprescribing, the safe withdrawal of medications, is a crucial part of optimizing patient care. Integrating deprescribing into prescribing ensures patients receive the most appropriate medicines and doses throughout their health journey.

Keywords:
deprescribingmedicines optimisationperson-centredshared decision making

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Area of Science:

  • Geriatrics
  • Clinical Pharmacy
  • Pharmacology

Background:

  • Deprescribing is a complex process with various approaches documented.
  • Current healthcare systems often prioritize prescribing over deprescribing.
  • Polypharmacy and unique patient medication experiences necessitate personalized reviews.

Purpose of the Study:

  • To highlight deprescribing as an integral component of prescribing.
  • To emphasize patient-centered medication reviews for optimal outcomes.
  • To underscore the importance of legal knowledge and consent in medication management.

Main Methods:

  • Review of existing literature on deprescribing guidelines and tools.
  • Analysis of the integration of deprescribing within healthcare systems.
  • Emphasis on shared decision-making and patient history in medication reviews.

Main Results:

  • International guidelines and tools exist to support safe medication withdrawal.
  • Deprescribing should be viewed as a continuous part of prescribing, not a separate activity.
  • Patient-centered reviews incorporating individual history are essential for medication optimization.

Conclusions:

  • Deprescribing is fundamental to ensuring patients remain on appropriate medications and doses.
  • Effective deprescribing requires integrating patient history, shared decision-making, and legal considerations.
  • Growing global networks facilitate research and best practice sharing in deprescribing.