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Updated: Jan 20, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Field triage for endovascular stroke therapy: a population-based comparison
Mahesh V Jayaraman1,2,3,4, Morgan L Hemendinger2, Grayson L Baird1,5
1Department of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Field triage to a comprehensive stroke center (CSC) for endovascular therapy (EVT) candidates resulted in faster treatment times and reduced disability. This strategy improves outcomes for stroke patients requiring urgent intervention.
Area of Science:
- Neurology
- Emergency Medicine
- Vascular Surgery
Background:
- Endovascular therapy (EVT) is a time-sensitive treatment for stroke.
- Optimizing patient transfer to stroke centers is crucial for improving outcomes.
Purpose of the Study:
- To compare treatment times and clinical outcomes.
- To evaluate field triage to a comprehensive stroke center (CSC) versus closest primary stroke center (PSC).
Main Methods:
- Retrospective analysis of 232 stroke patients over 2 years.
- Comparison of direct transport to PSC versus field triage to a more distant CSC.
- Matched-pairs analysis based on stroke severity and distance to CSC.
Main Results:
- Direct triage to CSC was associated with a median 7-minute increase in transport time.
- Faster times to alteplase and arterial puncture in the direct triage group (p<0.001).
- Reduced disability at 90 days for patients triaged directly to CSC (OR 1.47, p=0.003; matched pairs OR 2.06, p=0.01).
Conclusions:
- Field triage to a slightly more distant CSC improves time to EVT for eligible stroke patients.
- This strategy does not delay alteplase administration.
- Triage to CSC is associated with reduced patient disability at 90 days.
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