Related Experiment Video

Updated: Jan 20, 2026

Using Luciferase to Image Bacterial Infections in Mice
10:23

Using Luciferase to Image Bacterial Infections in Mice

Published on: February 18, 2011

21.0K

Molecular imaging of bacterial infections: Overcoming the barriers to clinical translation

Alvaro A Ordonez1,2,3, Mark A Sellmyer4,5, Gayatri Gowrishankar6

  • 1Center for Infection and Inflammation Imaging Research, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

Science Translational Medicine
|September 6, 2019
PubMed

More Related Videos

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes14:05

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes

Published on: September 19, 2013

10.3K
A Choroid Plexus Epithelial Cell-based Model of the Human Blood-Cerebrospinal Fluid Barrier to Study Bacterial Infection from the Basolateral Side09:58

A Choroid Plexus Epithelial Cell-based Model of the Human Blood-Cerebrospinal Fluid Barrier to Study Bacterial Infection from the Basolateral Side

Published on: May 6, 2016

14.8K

Related Concept Videos

Using Luciferase to Image Bacterial Infections in Mice10:23

Using Luciferase to Image Bacterial Infections in Mice

Methods for bioluminescence imaging of bacterial infections in living animals are decribed. Pathogens are modified to express luciferase allowing optical whole body imaging of infections in live animals. Animal models can be infected with luciferase expressing pathogens and the resulting course of disease visualized in real-time by bioluminescence...
21.0K
Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes14:05

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes

Listeria monocytogenes is a Gram positive bacterial pathogen frequently used as a major model for the study of intracellular parasitism. Imaging late L. monocytogenes infection stages within the context of small-interfering RNA screens allows for the global study of cellular pathways required for bacterial infection of target host...
10.3K
A Choroid Plexus Epithelial Cell-based Model of the Human Blood-Cerebrospinal Fluid Barrier to Study Bacterial Infection from the Basolateral Side09:58

A Choroid Plexus Epithelial Cell-based Model of the Human Blood-Cerebrospinal Fluid Barrier to Study Bacterial Infection from the Basolateral Side

The epithelial cells of the choroid plexus (CP) form the blood-cerebrospinal fluid barrier (BCSFB). An in vitro model of the BCSFB employs human choroid plexus papilloma (HIBCPP) cells. This article describes culturing and basolateral infection of HIBCPP cells using a cell culture filter insert...
14.8K
Reporter Enzyme Fluorescence Imaging for In Vivo Tracking of Bacterial Infection05:26

Reporter Enzyme Fluorescence Imaging for In Vivo Tracking of Bacterial Infection

This video demonstrates the reporter enzyme fluorescence (REF) imaging for in vivo detection of Mycobacterium tuberculosis infection. The infected mice are intraperitoneally injected with a substrate for REF imaging. Upon being hydrolyzed by bacterial β-lactamase enzyme, the substrate emits fluorescence, the detection of which aids evaluation of...
555
Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients13:50

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients

Our experiment will show how to perform a sequencing analysis of bacterial species translocating in peripheral blood of HIV positive patients.
12.7K
Fluorescence Imaging of Biomaterial-Associated Bacterial Infection in Zebrafish Embryos02:39

Fluorescence Imaging of Biomaterial-Associated Bacterial Infection in Zebrafish Embryos

Source: Zhang, X., et al. A Zebrafish Embryo Model for In Vivo Visualization and Intravital Analysis of Biomaterial-associated Staphylococcus aureus Infection. J. Vis. Exp. (2019)This video demonstrates fluorescence imaging of zebrafish embryos injected with Staphylococcus aureus, enabling quantification of infection progression and bacterial distribution to assess the impact of biomaterial microspheres on host-pathogen interactions in...
270